Hagen, Timo: search on Z-Library

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1

Intact Doxil is taken up intracellularly and released doxorubicin sequesters in the lysosome: Evaluated by in vitro/in vivo live cell imaging

Seynhaeve, Ann L.B., Dicheva, Bilyana M., Hoving, Saske, Koning, Gerben A., ten Hagen, Timo L.M.

Journal:

Journal of Controlled Release

Year:

2013

Language:

english

File:

PDF, 815 KB

english, 2013

2

Hyperthermia and Thermosensitive Liposomes for Improved Delivery of Chemotherapeutic Drugs to Solid Tumors

Gerben A. Koning, Alexander M. M. Eggermont, Lars H. Lindner, Timo L. M. ten Hagen

Journal:

Pharmaceutical Research

Year:

2010

Language:

english

File:

PDF, 308 KB

english, 2010

3

A novel two-step mild hyperthermia for advanced liposomal chemotherapy

Li, Li, ten Hagen, Timo L.M., Haeri, Azadeh, Soullié, Thomas, Scholten, Csilla, Seynhaeve, Ann L.B., Eggermont, Alexander M.M., Koning, Gerben A.

Journal:

Journal of Controlled Release

Year:

2014

Language:

english

File:

PDF, 1.65 MB

english, 2014

4

MR Angiography of Tumor-related Vasculature: From the Clinic to the Micro-environment1

van Vliet, Marion, van Dijke, Cornelis F., Wielopolski, Piotr A., ten Hagen, Timo L. M., Veenland, Jifke F., Preda, Anda, Loeve, Antonius J., Eggermont, Alexander M. M., Krestin, Gabriel P.

Journal:

Year:

2005

Language:

english

File:

PDF, 1.51 MB

english, 2005

5

Intravital Microscopy of Tumor-associated Vasculature Using Advanced Dorsal Skinfold Window Chambers on Transgenic Fluorescent Mice

Seynhaeve, Ann L.B., ten Hagen, Timo L.M.

Journal:

Journal of Visualized Experiments

Year:

2018

Language:

english

File:

PDF, 2.38 MB

english, 2018

6

Liposomes targeted to MHC-restricted antigen improve drug delivery and antimelanoma response

Saeed, Mesha, Zalba, Sara, Seynhaeve, Ann, Debets, Reno, ten Hagen, Timo L. M.

Journal:

International Journal of Nanomedicine

Year:

2019

Language:

english

File:

PDF, 2.69 MB

english, 2019

7

Targeted Photodynamic Therapy of Human Head and Neck Squamous Cell Carcinoma with Antiâepidermal Growth Factor Receptor Antibody Cetuximab and Photosensitizer IR700DX in the Mouse Skinâfold Window Chamber Model

Peng, Wei, de Bruijn, Henriette S., ten Hagen, Timo L.M., van Dam, Go M., Roodenburg, Jan L.N., Berg, Kristian, Witjes, Max J.H., Robinson, Dominic J.

Journal:

Photochemistry and Photobiology

Year:

2020

File:

PDF, 27.23 MB

2020

8

Biodistribution and tumor localization of stealth liposomal tumor necrosis factor-α in soft tissue sarcoma bearing rats

Alexander H. van der Veen, Alexander M. M. Eggermont, Ann L. B. Seynhaeve, Sandra T. van Tiel, Timo L. M. ten Hagen

Journal:

International Journal of Cancer

Year:

1998

Language:

english

File:

PDF, 98 KB

english, 1998

9

Tumor necrosis factor-alpha in isolated perfusion systems in the treatment of cancer: The Rotterdam Preclinical-Clinical Program

Eric R. Manusama, Peet T.G. A. Nooijen, Timo L.M. Ten Hagen, Alex H. Van Der Veen, Mark W. R. De Vries, Johannes H. W. De Wilt, Marc G. Van Ijken, Richard L. Marquet, Alexander M. M. Eggermont

Journal:

Seminars in Surgical Oncology

Year:

1998

Language:

english

File:

PDF, 46 KB

english, 1998

10

Low-dose tumor necrosis factor-α augments antitumor activity of stealth liposomal doxorubicin (DOXIL®) in soft tissue sarcoma-bearing rats

Timo L.M. Ten Hagen, Alexander H. Van Der Veen, Peet T.G.A. Nooijen, Sandra T. Van Tiel, Ann L.B. Seynhaeve, Alexander M.M. Eggermont

Journal:

International Journal of Cancer

Year:

2000

Language:

english

File:

PDF, 354 KB

english, 2000

11

Targeting of angiogenic endothelial cells at sites of inflammation by dexamethasone phosphate–containing RGD peptide liposomes inhibits experimental arthritis

Gerben A. Koning, Raymond M. Schiffelers, Marca H. M. Wauben, Robbert J. Kok, Enrico Mastrobattista, Grietje Molema, Timo L. M. ten Hagen, Gert Storm

Journal:

Arthritis & Rheumatism

Year:

2006

Language:

english

File:

PDF, 501 KB

english, 2006

12

Tumor necrosis factor-α augmented tumor response in B16BL6 melanoma-bearing mice treated with stealth liposomal doxorubicin (Doxil®) correlates with altered Doxil® pharmacokinetics

Peter Brouckaert, Nozomi Takahashi, Sandra T. van Tiel, Jeroen Hostens, Alexander M.M. Eggermont, Ann L.B. Seynhaeve, Walter Fiers, Timo L.M. ten Hagen

Journal:

International Journal of Cancer

Year:

2004

Language:

english

File:

PDF, 332 KB

english, 2004

13

Pegylated liposomal tumor necrosis factor-α results in reduced toxicity and synergistic antitumor activity after systemic administration in combination with liposomal doxorubicin (Doxil®) in soft tissue sarcoma-bearing rats

Timo L.M. ten Hagen, Ann L.B. Seynhaeve, Sandra T. van Tiel, Dirk J. Ruiter, Alexander M.M. Eggermont

Journal:

International Journal of Cancer

Year:

2002

Language:

english

File:

PDF, 337 KB

english, 2002

14

Intratumoural expression of TNF-R1 and EMAP-II in relation to response of patients treated with TNF-based isolated limb perfusion

Remco van Horssen, Joost A.P. Rens, Flavia Brunstein, Veronique Guns, Marjon van Gils, Timo L.M. ten Hagen, Alexander M.M. Eggermont

Journal:

International Journal of Cancer

Year:

2006

Language:

english

File:

PDF, 1.30 MB

english, 2006

15

Differential effects of matrix and growth factors on endothelial and fibroblast motility: Application of a modified cell migration assay

Remco van Horssen, Niels Galjart, Joost A.P. Rens, Alexander M.M. Eggermont, Timo L.M. ten Hagen

Journal:

Journal of Cellular Biochemistry

Year:

2006

Language:

english

File:

PDF, 836 KB

english, 2006

16

Crossing barriers: The new dimension of 2D cell migration assays

Remco van Horssen, Timo L.M. ten Hagen

Journal:

Journal of Cellular Physiology

Year:

2011

Language:

english

File:

PDF, 139 KB

english, 2011

17

Development of a liposomal delivery system for temperature-triggered release of a tumor targeting agent, Ln(III)-DOTA-phenylboronate

Kristina Djanashvili, Timo L.M. ten Hagen, Roy Blangé, Debby Schipper, Joop A. Peters, Gerben A. Koning

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 757 KB

english, 2011

18

In vivo micro particle image velocimetry measurements of blood-plasma in the embryonic avian heart

Peter Vennemann, Kenneth T. Kiger, Ralph Lindken, Bianca C.W. Groenendijk, Sandra Stekelenburg-de Vos, Timo L.M. ten Hagen, Nicolette T.C. Ursem, Rob E. Poelmann, Jerry Westerweel, Beerend P. Hierck

Journal:

Journal of Biomechanics

Year:

2006

Language:

english

File:

PDF, 520 KB

english, 2006

19

Stealth® liposomal tumor necrosis factor-α in solid tumor treatment

Alexander H van der Veen, Alexander M.M Eggermont, Timo L.M ten Hagen

Journal:

International Journal of Pharmaceutics

Year:

1998

Language:

english

File:

PDF, 86 KB

english, 1998

20

Liposomes as delivery systems in the prevention and treatment of infectious diseases

Joep J. Bergers, Timo L. M. ten Hagen, Els W. M. van Etten, Irma A. J. M. Bakker-Woudenberg

Journal:

International Journal of Clinical Pharmacy

Year:

1995

Language:

english

File:

PDF, 1.97 MB

english, 1995

21

Perfusión de extremidad aislada en Oncología

Emiliano Calvo Aller, Ramón Arcas Meca, Aurora Crespo de la Jara, Antonio Brugarolas Masllorens, Timo LM ten Hagen, Alexander MM Eggermont

Journal:

Clinical and Translational Oncology

Year:

2003

File:

PDF, 189 KB

2003

22

Decreased response rates by the combination of histamine and IL-2 in melphalan-based isolated limb perfusion

Flavia Brunstein, Saske Hoving, Gisela aan de Wiel-Ambagtsheer, Ernst A. de Bruijn, Gunther Guetens, Alexander M. M. Eggermont, Timo L. M. ten Hagen

Journal:

Cancer Immunology, Immunotherapy

Year:

2007

Language:

english

File:

PDF, 506 KB

english, 2007

23

Combination of IL-21 and IL-15 enhances tumour-specific cytotoxicity and cytokine production of TCR-transduced primary T cells

Nadine Pouw, Elike Treffers-Westerlaken, Jaco Kraan, Floyd Wittink, Timo ten Hagen, Jaap Verweij, Reno Debets

Journal:

Cancer Immunology, Immunotherapy

Year:

2010

Language:

english

File:

PDF, 536 KB

english, 2010

24

Serum concentrations of pegylated interferon α-2b in patients with resected stage III melanoma receiving adjuvant pegylated interferon α-2b in a randomized phase III trial (EORTC 18991)

Alexander M. M. Eggermont, Marna G. Bouwhuis, Wim H. Kruit, Alessandro Testori, Timo ten Hagen, Antoine Yver, Christine Xu

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2010

Language:

english

File:

PDF, 341 KB

english, 2010

25

Systemic Toxicity and Cytokine/Acute Phase Protein Levels in Patients After Isolated Limb Perfusion With Tumor Necrosis Factor-a Complicated by High Leakage

Tanja C. Stam, Anton J. G. Swaak, Mark R. de Vries, Timo L. M. ten Hagen, Alexander M. M. Eggermont

Journal:

Annals of Surgical Oncology

Year:

2000

Language:

english

File:

PDF, 98 KB

english, 2000

26

EMAP-II facilitates TNF-R1 apoptotic signalling in endothelial cells and induces TRADD mobilization

Remco van Horssen, Joost A. P. Rens, Debby Schipper, Alexander M. M. Eggermont, Timo L. M. ten Hagen

Journal:

Year:

2006

Language:

english

File:

PDF, 550 KB

english, 2006

27

Isolated Limb Perfusion with Melphalan and TNF-α in the Treatment of Extremity Sarcoma

Cornelis Verhoef, Johannes H. W. de Wilt, Dirk J. Grünhagen, Albertus N. van Geel, Timo L. M. ten Hagen, Alexander M. M. Eggermont

Journal:

Current Treatment Options in Oncology

Year:

2007

Language:

english

File:

PDF, 333 KB

english, 2007

28

Isolated limb perfusion for extremity soft-tissue sarcomas, in-transit metastases, and other unresectable tumors: Credits, debits, and future perspectives

Alexander M. M. Eggermont, Timo L. M. ten Hagen

Journal:

Current Oncology Reports

Year:

2001

Language:

english

File:

PDF, 500 KB

english, 2001

29

Tumor necrosis factor-based isolated limb perfusion for soft tissue sarcoma and melanoma: Ten years of successful antivascular therapy

Alexander M. M. Eggermont, Timo L. M. ten Hagen

Journal:

Current Oncology Reports

Year:

2003

Language:

english

File:

PDF, 103 KB

english, 2003

30

Tumor necrosis factor-mediated interactions between inflammatory response and tumor vascular bed

Timo L. M. Ten Hagen, Ann L. B. Seynhaeve, Alexander M. M. Eggermont

Journal:

Immunological Reviews

Year:

2008

Language:

english

File:

PDF, 341 KB

english, 2008

31

Differential nitric oxide and TNF-α production of murine Kupffer cell subfractions upon priming with IFN-γ and TNF-α

Timo L. M. Ten Hagen, Wim Van Vianen, Hubertine Heremans, Irma A. J. M. Bakker-Woudenberg

Journal:

Liver International

Year:

1998

Language:

english

File:

PDF, 880 KB

english, 1998

32

A K+-selective cGMP-gated ion channel controls chemosensation of sperm

Strünker, Timo, Weyand, Ingo, Bönigk, Wolfgang, Van, Qui, Loogen, Astrid, Brown, Joel E., Kashikar, Nachiket, Hagen, Volker, Krause, Eberhard, Kaupp, U.Benjamin

Journal:

Nature Cell Biology

Year:

2006

Language:

english

File:

PDF, 1.08 MB

english, 2006

33

Vasoactive peptides upregulate mRNA expression and secretion of vascular endothelial growth factor in human airway smooth muscle cells

Vijay K. T. Alagappan, Anna Willems-Widyastuti, Ann L. B. Seynhaeve, Ingrid M. Garrelds, Timo L. M. ten Hagen, Pramod R. Saxena, Hari S. Sharma

Journal:

Cell Biochemistry and Biophysics

Year:

2007

Language:

english

File:

PDF, 424 KB

english, 2007

34

Synergistic Antitumor Effects of Histamine Plus Melphalan in Isolated Hepatic Perfusion for Liver Metastases

Flavia Brunstein, Alexander M. M. Eggermont, Gisela aan de Wiel-Ambagtsheer, Sandra T. van Tiel, Joost Rens, Timo L. M. ten Hagen

Journal:

Annals of Surgical Oncology

Year:

2007

Language:

english

File:

PDF, 324 KB

english, 2007

35

Isolation and characterization of murine Kupffer cells and splenic macrophages

Timo L.M. ten Hagen, Wim Van Vianen, Irma A.J.M. Bakker-Woudenberg

Journal:

Journal of Immunological Methods

Year:

1996

Language:

english

File:

PDF, 1.04 MB

english, 1996

36

Role of CLASP2 in Microtubule Stabilization and the Regulation of Persistent Motility

Ksenija Drabek, Marco van Ham, Tatiana Stepanova, Katharina Draegestein, Remco van Horssen, Carmen Laura Sayas, Anna Akhmanova, Timo ten Hagen, Ron Smits, Riccardo Fodde, Frank Grosveld, Niels Galjart

Journal:

Current Biology

Year:

2006

Language:

english

File:

PDF, 1.25 MB

english, 2006

37

Triggered content release from optimized stealth thermosensitive liposomes using mild hyperthermia

Li Li, Timo L.M. ten Hagen, Debby Schipper, Tom M. Wijnberg, Gerard C. van Rhoon, Alexander M.M. Eggermont, Lars H. Lindner, Gerben A. Koning

Journal:

Journal of Controlled Release

Year:

2010

Language:

english

File:

PDF, 882 KB

english, 2010

38

Anti-tumor efficacy of tumor vasculature-targeted liposomal doxorubicin

Raymond M Schiffelers, Gerben A Koning, Timo L.M ten Hagen, Marcel H.A.M Fens, Astrid J Schraa, Adriënne P.C.A Janssen, Robbert J Kok, Grietje Molema, Gert Storm

Journal:

Journal of Controlled Release

Year:

2003

Language:

english

File:

PDF, 242 KB

english, 2003

39

A rat extremity soft tissue sarcoma model for the study of systemic treatment with Stealth® liposome-encapsulated tumor necrosis factor-α and cytotoxic agents

Timo L.M. ten Hagen, Alexander M.M. Eggermont

Journal:

Advanced Drug Delivery Reviews

Year:

1997

Language:

english

File:

PDF, 1.51 MB

english, 1997

40

Endothelial monocyte-activating polypeptide-II and its functions in (patho)physiological processes

Remco van Horssen, Alexander M.M. Eggermont, Timo L.M. ten Hagen

Journal:

Cytokine & Growth Factor Reviews

Year:

2006

Language:

english

File:

PDF, 906 KB

english, 2006

41

Differential expression and prognostic value of HMGA1 in pancreatic head and periampullary cancer

Jill A. van der Zee, Timo L.M. ten Hagen, Wim C.J. Hop, Herman van Dekken, Bilyana M. Dicheva, Ann L.B. Seynhaeve, Gerben A. Koning, Alexander M.M. Eggermont, Casper H.J. van Eijck

Journal:

European Journal of Cancer

Year:

2010

Language:

english

File:

PDF, 659 KB

english, 2010

42

Angiogenesis: A prognostic determinant in pancreatic cancer?

Jill A. van der Zee, Casper H.J. van Eijck, Wim C.J. Hop, Herman van Dekken, Bilyana M. Dicheva, Ann L.B. Seynhaeve, Gerben A. Koning, Alexander M.M. Eggermont, Timo L.M. ten Hagen

Journal:

European Journal of Cancer

Year:

2011

Language:

english

File:

PDF, 1.05 MB

english, 2011

43

Serum amino acids, biopterin and neopterin during long-term immunotherapy with interferon-alpha in high-risk melanoma patients

Arthur R. Van Gool, Durk Fekkes, Wim H.J. Kruit, Paul G.H. Mulder, Timo L.M. Ten Hagen, Marjolein Bannink, Michael Maes, Alexander M.M. Eggermont

Journal:

Psychiatry Research

Year:

2003

Language:

english

File:

PDF, 92 KB

english, 2003

44

In vivo observations on angiogenesis and vasodestruction in tumor window models

Timo L.M. ten Hagen

Journal:

European Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 95 KB

english, 2001

45

Current uses of isolated limb perfusion in the clinic and a model system for new strategies

Alexander MM Eggermont, Johannes HW de Wilt, Timo LM ten Hagen

Journal:

The Lancet Oncology

Year:

2003

Language:

english

File:

PDF, 1.52 MB

english, 2003

46

TNF is here to stay — revisited

Timo L.M ten Hagen, Alexander M.M Eggermont, Ferdy J Lejeune

Journal:

Trends in Immunology

Year:

2001

Language:

english

File:

PDF, 33 KB

english, 2001

47

E-cadherinpromotor methylation and mutation are inversely related to motility capacity of breast cancer cells

Remco van Horssen, Antoinette Hollestelle, Joost A. P. Rens, Alexander M. M. Eggermont, Mieke Schutte, Timo L. M. ten Hagen

Journal:

Breast Cancer Research and Treatment

Year:

2012

Language:

english

File:

PDF, 1016 KB

english, 2012

48

Immunologic functions as prognostic indicators in melanoma

Marna G. Bouwhuis, Timo L.M. ten Hagen, Alexander M.M. Eggermont

Journal:

Molecular Oncology

Year:

2011

Language:

english

File:

PDF, 187 KB

english, 2011

49

Improved intratumoral nanoparticle extravasation and penetration by mild hyperthermia

Li, Li, ten Hagen, Timo L.M., Bolkestein, Michiel, Gasselhuber, Astrid, Yatvin, Jeremy, van Rhoon, Gerard C., Eggermont, Alexander M.M., Haemmerich, Dieter, Koning, Gerben A.

Journal:

Journal of Controlled Release

Year:

2013

Language:

english

File:

PDF, 1.69 MB

english, 2013

50

Mild hyperthermia triggered doxorubicin release from optimized stealth thermosensitive liposomes improves intratumoral drug delivery and efficacy

Li, Li, ten Hagen, Timo L.M., Hossann, Martin, Süss, Regine, van Rhoon, Gerard C., Eggermont, Alexander M.M., Haemmerich, Dieter, Koning, Gerben A.

Journal:

Journal of Controlled Release

Year:

2013

Language:

english

File:

PDF, 1.29 MB

english, 2013

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